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This book provides readers an extensive overview of recent progress in basic and clinical research on cancer immunotherapy. Thanks to rapid advances in molecular biology and immunology, it has become increasingly evident that cancer growth is influenced by host immune responses. With the success of a number of clinical trials, immunotherapy has become a promising treatment modality of cancer. This book covers five major topics, including monoclonal antibodies, biological response modifiers, cancer vaccines, adoptive cellular therapy and oncolytic viruses. It also examines the combination of different immune strategies as well as the combination of immunotherapy with other treatments to increase anti-tumor effects. Through the comprehensive discussion of the topic, the book sheds valuable new light on the treatment of tumors.
With over 200 types of cancer diagnosed to date, researchers the world over have been forced to rapidly update their understanding of the biology of cancer. In fact, only the study of the basic cellular processes, and how these are altered in cancer cells, can ultimately provide a background for rational therapies. Bringing together the state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate research goal for the whole scientific community: exploiting systems biology to generate in-depth knowledge based on blueprints that are unique to each type of cancer. Readers are provided with a realistic view of what is known and what is yet to be uncovered on the aberrations in the fundamental biological processes, deregulation of major signaling networks, alterations in major cancers and the strategies for using the scientific knowledge for effective diagnosis, prognosis and drug discovery to improve public health.
The classic surgical atlas, more comprehensive than ever!
For more than half-a-century, Zollinger’s Atlas of Surgical Operations has been the gold-standard reference for learning how to perform the most common surgical procedures using safe, well-established techniques. The tenth edition continues this tradition of excellence. The atlas covers gastrointestinal, hepatobiliary, pancreatic, vascular, gynecologic, and additional procedures, including hernia repair, vascular access, breast procedures, sentinel lymph node biopsy,thyroidectomy, and many more. The illustrations in this atlas have withstood the test of time. They allow you to visualize both the anatomy and the operation, making the book useful as a refresher or for learning the steps of a particular procedure.
The tenth edition of Zollinger’s Atlas of Surgical Operations expands the content to include 19 new operations. Each chapter contains beautifully rendered line drawings with color highlights that depict every important action you must consider while performing the operation. Each chapter also includes consistently formatted coverage of indications,preoperative preparation, anesthesia, position, operative preparation, incision and exposure, procedure, closure, and postoperative care.
Following in the footsteps of the previous two volumes, this third volume of the Alexander Discipline, focusing on unusual and difficult cases, demonstrates through the presentation of complete patient records how these principles can be used to achieve beautiful, functional, and stable results even in patients requiring creative treatment planning and treatment mechanics. In the situations presented in this book, there is no one right answer to the problem, and the orthodontist must have the confidence and relevant knowledge to formulate the treatment plan most suitable for each patient.
This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.
Read it – Ken Saladin explains human anatomy in an engaging, yet efficient way. He puts a premium on the words, and uses student–relevant analogies to motivate the reader.
See it – Saladin’s collection of illustrations and photos are carefully chosen to support the text discussion. Vibrant and realistic presentations engage students.
Master it – With Connect Anatomy and Physiology, Learn Smart and Anatomy and Physiology Revealed, students can practice and improve their understanding of concepts.
From the most pedagogically sound organisation to the exceptional art, to the integration of text with technology, Saladin has formed a teaching system that will both motivate and enable students to understand and appreciate the wonders of human anatomy. This distinctive text was developed to stand apart from all other anatomy texts with an approach borne out of more than 30 years of teaching, unparalleled art, and a writing style that has been acclaimed by reviewers. Designed for a one–semester college anatomy course, Saladin requires no prior knowledge of chemistry or cell biology.